Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18394802 | 0.87 | CNR2 (0.44) | ALDH1A1HSD17B10CFTRUSP2MAPK1 | |
| SCHEMBL29664577 | 0.87 | CNR2 (0.44) | ALDH1A1HSD17B10CFTRUSP2MAPK1 | |
| SCHEMBL13557127 | 0.85 | MAPK1 (0.44) | ALDH1A1HSD17B10CFTRUSP2MAPK1 | |
| SCHEMBL1078681 | 0.84 | MAPK1 (0.39) | ALDH1A1HSD17B10CFTRUSP2MAPK1 | |
| SCHEMBL1080174 | 0.83 | MAPK1 (0.38) | ALDH1A1HSD17B10CFTRUSP2MAPK1 | |
| SCHEMBL1077377 | 0.81 | NR4A2 (0.39) | ALDH1A1HSD17B10CFTRUSP2MAPK1 | |
| SCHEMBL12584098 | 0.80 | KDM4E (0.41) | ALDH1A1USP2MAPK1TSHRKDM4E | |
| SCHEMBL22800161 | 0.80 | CYP3A4 (0.38) | ALDH1A1HSD17B10USP2MAPK1LMNA | |
| SCHEMBL12584050 | 0.80 | KDM4E (0.47) | ALDH1A1HSD17B10TSHRKDM4EMAPT | |
| SCHEMBL12750465 | 0.80 | KDM4E (0.43) | ALDH1A1HSD17B10CFTRUSP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011008572-A2 | 5-HT3 RECEPTOR MODULATORS, METHODS OF MAKING, AND USE THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-01-20 | — | — | WO | disclosed |