Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506919 | 0.84 | DDB1 (0.56) | DDB1CRBNMCHR1HCRTR1HCRTR2 | |
| SCHEMBL9050436 | 0.81 | MCHR1 (0.57) | DDB1CRBNMCHR1HCRTR1HCRTR2 | |
| SCHEMBL4887893 | 0.81 | MCHR1 (0.61) | DDB1CRBNMCHR1HCRTR1HCRTR2 | |
| SCHEMBL6922462 | 0.80 | MCHR1 (0.51) | DDB1CRBNMCHR1HCRTR1HCRTR2 | |
| SCHEMBL6919858 | 0.80 | MCHR1 (0.51) | DDB1CRBNMCHR1HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL9051831 | 0.80 | MCHR1 (0.56) | DDB1CRBNMCHR1HCRTR1HCRTR2 | |
| SCHEMBL9632180 | 0.80 | MCHR1 (0.64) | DDB1CRBNMCHR1HCRTR1HCRTR2 | |
| SCHEMBL3129814 | 0.79 | DDB1 (0.51) | DDB1CRBNMCHR1HCRTR1HCRTR2 | |
| SCHEMBL3715640 | 0.77 | DDB1 (0.53) | DDB1CRBNMCHR1KDM4EMAPT | |
| SCHEMBL20064518 | 0.74 | SLC9A3 (0.48) | DDB1CRBNMCHR1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099185-A1 | 2-CYANOPYRROLIDINE DERIVATIVES AND THEIR USE AS DPP-IV INHIBITORS | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-11-18 | — | — | WO | disclosed |