Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 14/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920391 | 1.00 | PTGER4 (0.55) | PTGER4PTGER2PTGER3 | |
| SCHEMBL6920397 | 1.00 | PTGER4 (0.55) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5815153 | 0.86 | PTGER4 (0.73) | PTGER4PTGER2PTGER3 | |
| SCHEMBL6683757 | 0.86 | PTGER4 (0.73) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5815150 | 0.86 | PTGER4 (0.73) | PTGER4PTGER2PTGER3 | |
| SCHEMBL2244704 | 0.82 | PTGER4 (0.66) | PTGER4PTGER2PTGER3 | |
| SCHEMBL2244711 | 0.82 | PTGER4 (0.66) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5953696 | 0.82 | PTGER4 (0.42) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5953704 | 0.82 | PTGER4 (0.42) | PTGER4PTGER2PTGER3 | |
| SCHEMBL6794309 | 0.79 | PTGER4 (0.74) | PTGER4PTGER2PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037813-A1 | PYRROLIDIN-2-ON DERIVATIVES AS EP4 RECEPTOR AGONISTS | MERCK FROSST CANADA & CO. (CA) | 2004-05-06 | — | — | WO | claimed |
| WO-2004037813-A1 | PYRROLIDIN-2-ON DERIVATIVES AS EP4 RECEPTOR AGONISTS | MERCK FROSST CANADA & CO. (CA) | 2004-05-06 | — | — | WO | disclosed |