Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | KRAS | P01116 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18383120 | 0.88 | MAPT (0.69) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL3078541 | 0.88 | HTT (0.57) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL11037210 | 0.86 | KRAS (0.56) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL31744696 | 0.86 | MAPT (0.54) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL4053484 | 0.86 | MAPT (0.54) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL693485 | 0.86 | PTGS1 (0.60) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL31558741 | 0.85 | MAPT (0.53) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL4051892 | 0.85 | PTPN5 (0.62) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL4443613 | 0.84 | MAPT (0.51) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL10806849 | 0.82 | ATM (0.54) | MAPTCYP3A4ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501165-B | Asymmetric synthesis method of chiral tetrahydrocarbazole derivative | 合肥工业大学 | 2020-03-31 | — | — | CN | claimed |
| CN-107501165-A | The method of asymmetric synthesis of chiral compounds | 合肥工业大学 | 2017-12-22 | — | — | CN | claimed |
| CN-114956932-B | Synthesis method of polysubstituted chiral tetrahydroquinoline compound | 东北大学秦皇岛分校 | 2023-11-10 | — | — | CN | disclosed |
| CN-114956932-A | Synthesis method of polysubstituted chiral tetrahydroquinoline compound | 东北大学秦皇岛分校 | 2022-08-30 | — | — | CN | disclosed |
| CN-107501165-B | Asymmetric synthesis method of chiral tetrahydrocarbazole derivative | 合肥工业大学 | 2020-03-31 | — | — | CN | disclosed |
| CN-107501165-A | The method of asymmetric synthesis of chiral compounds | 合肥工业大学 | 2017-12-22 | — | — | CN | disclosed |
| CN-104804004-B | A kind of preparation method of chiral hexahydropyrrolo diindyl class compound | 安徽师范大学 | 2017-03-29 | — | — | CN | disclosed |
| WO-2004096766-A1 | A METHOD OF INDOLE SYNTHESIS | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2004-11-11 | — | — | WO | disclosed |