Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 13/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1867804 | 0.94 | ADORA1 (0.65) | ADORA1ADORA2AADORA2BADORA3SLC6A3 | |
| SCHEMBL1877354 | 0.82 | ADORA1 (0.58) | ADORA1ADORA2AADORA2BADORA3SLC6A3 | |
| SCHEMBL12079939 | 0.79 | ADORA1 (0.55) | ADORA1ADORA2AADORA2BADORA3SLC6A3 | |
| SCHEMBL12079866 | 0.79 | ADORA1 (0.66) | ADORA1ADORA2AADORA2BADORA3SLC6A3 | |
| SCHEMBL1868606 | 0.78 | ADORA1 (0.64) | ADORA1ADORA2AADORA2BADORA3SLC6A3 | |
| SCHEMBL1868133 | 0.74 | ADORA1 (0.49) | ADORA1ADORA2AADORA2BADORA3SLC6A3 | |
| SCHEMBL7269366 | 0.73 | ADORA1 (1.00) | ADORA1ADORA2AADORA2BADORA3SLC6A3 | |
| SCHEMBL1866029 | 0.73 | ADORA1 (0.57) | ADORA1ADORA2AADORA2BADORA3SLC6A3 | |
| SCHEMBL6921078 | 0.73 | ADORA1 (0.45) | ADORA1ADORA2AADORA2BADORA3SLC6A3 | |
| SCHEMBL1864553 | 0.71 | ADORA1 (0.55) | ADORA1ADORA2AADORA2BADORA3SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011055391-A1 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS, ITS PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-05-12 | — | — | WO | disclosed |