Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1487645 | 0.86 | GRM5 (0.56) | GRM5CYP3A4 | |
| SCHEMBL1981351 | 0.82 | GRM5 (0.59) | GRM5CYP3A4 | |
| SCHEMBL6919814 | 0.81 | GRM5 (0.55) | GRM5CYP3A4 | |
| SCHEMBL6919417 | 0.76 | GRM5 (0.65) | GRM5CYP3A4 | |
| SCHEMBL2182610 | 0.75 | GRM5 (0.43) | GRM5CYP3A4 | |
| SCHEMBL6918719 | 0.74 | CYP3A4 (0.81) | GRM5CYP3A4 | |
| SCHEMBL7448823 | 0.73 | PARP1 (0.55) | — | |
| SCHEMBL6918743 | 0.73 | GRM5 (0.62) | GRM5CYP3A4 | |
| SCHEMBL6919023 | 0.73 | GRM5 (0.82) | GRM5CYP3A4 | |
| SCHEMBL2180716 | 0.73 | GRM5 (0.52) | GRM5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011035209-A1 | SUBSTITUTED BENZAMIDE ANALOGS AS MGLUR5 NEGATIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING THE SAME | VANDERBILT UNIVERSTIY (US) | 2011-03-24 | — | — | WO | disclosed |