⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269174 | 0.65 | — | — | |
| SCHEMBL7447408 | 0.62 | — | — | |
| SCHEMBL363991 | 0.62 | — | — | |
| SCHEMBL3630407 | 0.60 | — | — | |
| SCHEMBL2598094 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL18398546 | 0.60 | — | — | |
| SCHEMBL15956217 | 0.57 | — | — | |
| SCHEMBL19411844 | 0.57 | — | — | |
| SCHEMBL775375 | 0.57 | — | — | |
| Hydrochloric Acid SCHEMBL19207995 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2853534-A1 | Novel nitrogenous heterocyclic compounds, preparation thereof and use of same as antibacterial drugs | ASTRA ZENECA HOLDING FRANCE (FR) | 2015-04-01 | — | — | EP | claimed |
| WO-2010041108-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF, AND USE THEREOF AS ANTIBACTERIAL AGENTS | NOVEXEL (FR) | 2010-04-15 | — | — | WO | claimed |
| EP-1931672-A1 | NOVEL 5,6-DIHYDROPYRAZOLO[3,4-E] [L,4]DIAZEPIN-4 (IH) -ONE DERIVATIVES FOR THE TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE. | AstraZeneca AB (SE) | 2008-06-18 | — | — | EP | claimed |
| WO-2007040435-A1 | NOVEL 5,6-DIHYDROPYRAZOLO[3,4-E] [L,4]DIAZEPIN-4 (IH) -ONE DERIVATIVES FOR THE TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE. | ASTRAZENECA AB (SE) | 2007-04-12 | — | — | WO | claimed |
| EP-4289845-A1 | TRIHETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022223022-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-10-27 | — | — | WO | disclosed |
| EP-2853534-A1 | Novel nitrogenous heterocyclic compounds, preparation thereof and use of same as antibacterial drugs | ASTRA ZENECA HOLDING FRANCE (FR) | 2015-04-01 | — | — | EP | disclosed |
| EP-2845855-A1 | Novel nitrogenous heterocyclic compounds, preparation thereof and use of same as antibacterial drugs | ASTRA ZENECA HOLDING FRANCE (FR) | 2015-03-11 | — | — | EP | disclosed |
| EP-2421870-A2 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | Abbott Laboratories (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-2358722-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF, AND USE THEREOF AS ANTIBACTERIAL AGENTS | NOVEXEL (FR) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010124042-A2 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010041108-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF, AND USE THEREOF AS ANTIBACTERIAL AGENTS | NOVEXEL (FR) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010038115-A1 | NOVEL NITROGENOUS HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND USE THEREOF AS ANTIBACTERIAL MEDICAMENTS | NOVEXEL (FR) | 2010-04-08 | — | — | WO | disclosed |
| EP-1931672-A1 | NOVEL 5,6-DIHYDROPYRAZOLO[3,4-E] [L,4]DIAZEPIN-4 (IH) -ONE DERIVATIVES FOR THE TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE. | AstraZeneca AB (SE) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007040435-A1 | NOVEL 5,6-DIHYDROPYRAZOLO[3,4-E] [L,4]DIAZEPIN-4 (IH) -ONE DERIVATIVES FOR THE TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE. | ASTRAZENECA AB (SE) | 2007-04-12 | — | — | WO | disclosed |
| EP-0288201-A1 | Process for the preparation of benzodiazepines | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-10-26 | — | — | EP | disclosed |