Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.41 |
| ▸ | KDR | P35968 | 5/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920438 | 0.96 | GRM2 (0.46) | GRM2FLT3GRIN2BKDRFGFR3 | |
| SCHEMBL15865814 | 0.84 | GRM5 (0.48) | — | |
| SCHEMBL12059189 | 0.82 | FLT3 (0.45) | GRM2FLT3GRIN2BKDRFGFR3 | |
| SCHEMBL6922507 | 0.80 | FLT3 (0.43) | GRM2FLT3GRIN2BKDRFGFR3 | |
| SCHEMBL6921936 | 0.80 | FLT3 (0.44) | GRM2FLT3GRIN2BKDRFGFR3 | |
| SCHEMBL6922604 | 0.80 | FLT3 (0.43) | GRM2FLT3GRIN2BKDRFGFR3 | |
| SCHEMBL15865813 | 0.80 | GRM5 (0.45) | — | |
| SCHEMBL6922510 | 0.80 | KDR (0.48) | GRM2FLT3GRIN2BKDRFGFR3 | |
| SCHEMBL6922096 | 0.79 | FLT3 (0.44) | GRM2FLT3GRIN2BKDRFGFR3 | |
| SCHEMBL6920749 | 0.77 | FLT3 (0.42) | GRM2FLT3GRIN2BKDRFGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075699-A2 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2011-06-23 | — | — | WO | disclosed |