Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PREP | P48147 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19414714 | 0.88 | CHRM2 (0.47) | CHRM2CHRM1CHRM3PREP | |
| SCHEMBL16549901 | 0.85 | CHRM2 (0.47) | CHRM2CHRM1CHRM3PREP | |
| SCHEMBL15281913 | 0.85 | CHRM2 (0.47) | CHRM2CHRM1CHRM3PREP | |
| SCHEMBL15348379 | 0.85 | CHRM2 (0.47) | CHRM2CHRM1CHRM3PREP | |
| SCHEMBL16592244 | 0.85 | CHRM2 (0.47) | CHRM2CHRM1CHRM3PREP | |
| SCHEMBL14486578 | 0.85 | CHRM2 (0.47) | CHRM2CHRM1CHRM3PREP | |
| SCHEMBL29514321 | 0.85 | CHRM2 (0.47) | CHRM2CHRM1CHRM3PREP | |
| SCHEMBL25183803 | 0.85 | CHRM2 (0.46) | CHRM2CHRM1CHRM3PREP | |
| SCHEMBL17311996 | 0.85 | CHRM2 (0.46) | CHRM2CHRM1CHRM3PREP | |
| SCHEMBL12050947 | 0.85 | CHRM2 (0.46) | CHRM2CHRM1CHRM3PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111041-A1 | PYRROLIDINE, THIAZOLIDINE AND OXAZOLIDINE COMPOUNDS WHICH INHIBIT DIPEPTIDYL PEPTIDASE-IV (DPP) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-23 | — | — | WO | disclosed |