Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 4/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560311 | 0.98 | TP53 (0.63) | TP53OPRM1CA1SPHK1LAP3 | |
| SCHEMBL2053835 | 0.98 | TP53 (0.63) | TP53OPRM1CA1SPHK1LAP3 | |
| SCHEMBL8677764 | 0.98 | TP53 (0.63) | TP53OPRM1CA1SPHK1LAP3 | |
| SCHEMBL8971518 | 0.98 | TP53 (0.63) | TP53OPRM1CA1SPHK1LAP3 | |
| SCHEMBL10891420 | 0.98 | TP53 (0.63) | TP53OPRM1CA1SPHK1LAP3 | |
| SCHEMBL4662306 | 0.98 | TP53 (0.63) | TP53OPRM1CA1SPHK1LAP3 | |
| SCHEMBL2053107 | 0.98 | TP53 (0.63) | TP53OPRM1CA1SPHK1LAP3 | |
| SCHEMBL2052450 | 0.98 | TP53 (0.63) | TP53OPRM1CA1SPHK1LAP3 | |
| SCHEMBL8497172 | 0.98 | TP53 (0.63) | TP53OPRM1CA1SPHK1LAP3 | |
| SCHEMBL27568395 | 0.98 | TP53 (0.63) | TP53OPRM1CA1SPHK1LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801974-B | Process for the manufacture of bridged monobactam intermediates | BASILEA PHARMACEUTICA AG | 2013-08-28 | — | — | CN | claimed |
| CN-101801974-A | Process for the manufacture of bridged monobactam intermediates | BASILEA PHARMACEUTICA AG | 2010-08-11 | — | — | CN | claimed |
| US-5698577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1997-12-16 | — | — | US | claimed |
| US-5510343-A | BETA-LACTAMASE INHIBITOR | HOFFMANN-LA ROCHE INC. (US) | 1996-04-23 | — | — | US | claimed |
| CN-113272306-A | Chemical compound | 爱维斯塔制药解决方案有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-104922128-B | Inhibitors of influenza virus replication | 沃泰克斯药物股份有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-110540538-A | Inhibitors of influenza virus replication | VERTEX PHARMA | 2019-12-06 | — | — | CN | disclosed |
| US-9757367-B2 | Calcium propane-2-sulfinate dihydrate | AMGEN INC. (US) | 2017-09-12 | — | — | US | disclosed |
| US-9623018-B2 | Processes of making and crystalline forms of a MDM2 inhibitor | AMGEN INC. (US) | 2017-04-18 | — | — | US | disclosed |
| CN-104940202-A | Inhibitors of influenza viruses replication | VERTEX PHARMA | 2015-09-30 | — | — | CN | disclosed |
| CN-103724330-B | The effective combined utilization of monobactams antibiotic and beta-lactamase inhibitor | BASLIER PHARMACEUTICAL AG (CH) | 2015-08-19 | — | — | CN | disclosed |
| CN-102458408-B | Inhibitors of influenza virus replication | VERTEX PHARMA | 2015-06-03 | — | — | CN | disclosed |
| US-5698577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5663201-A | COMPLEXES WITH IRON OR ALUMINUM | CIBA-GEIGY CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| US-5512679-A | Process for the preparation of 2-aryl-ethane-sulphonic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-30 | — | — | US | disclosed |
| US-5510343-A | BETA-LACTAMASE INHIBITOR | HOFFMANN-LA ROCHE INC. (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |
| EP-0075318-A2 | p-Hydroxyphenylglycine alpha-phenylethanesulfonate, process for production thereof and utilization thereof in resolution of p-hydroxyphenylglycine | Tanabe Seiyaku Co., Ltd. (JP) | 1983-03-30 | — | — | EP | disclosed |