Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 19/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922907 | 0.87 | GRM5 (0.45) | GRM5 | |
| SCHEMBL15865811 | 0.87 | GRM5 (0.45) | GRM5 | |
| SCHEMBL6922582 | 0.86 | GRM5 (0.47) | GRM5 | |
| SCHEMBL6922278 | 0.83 | GRM5 (0.41) | GRM5 | |
| SCHEMBL6922848 | 0.82 | GRM5 (0.42) | GRM5 | |
| SCHEMBL6921584 | 0.79 | GRM5 (0.42) | GRM5 | |
| SCHEMBL6923279 | 0.78 | GRM5 (0.41) | GRM5 | |
| SCHEMBL6920768 | 0.78 | GRM5 (0.42) | GRM5 | |
| SCHEMBL6920971 | 0.77 | GRM5 (0.39) | GRM5 | |
| SCHEMBL6920618 | 0.77 | CHRM5 (0.40) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075699-A2 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2011-06-23 | — | — | WO | disclosed |