Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 5/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921954 | 0.90 | POLB (0.46) | POLBPTPN7DUSP3RXFP1NPC1 | |
| SCHEMBL14240282 | 0.87 | POLB (0.41) | POLBPTPN7DUSP3RXFP1NPC1 | |
| SCHEMBL2052700 | 0.85 | POLB (0.44) | POLBPTPN7DUSP3RXFP1NPC1 | |
| SCHEMBL9994196 | 0.84 | POLB (0.42) | POLBPTPN7DUSP3RXFP1NPC1 | |
| SCHEMBL6922456 | 0.82 | POLB (0.44) | POLBPTPN7DUSP3RXFP1NPC1 | |
| SCHEMBL2046075 | 0.82 | POLB (0.44) | POLBPTPN7DUSP3RXFP1NPC1 | |
| SCHEMBL2046073 | 0.82 | POLB (0.44) | POLBPTPN7DUSP3RXFP1NPC1 | |
| SCHEMBL9994524 | 0.82 | POLB (0.44) | POLBPTPN7DUSP3RXFP1NPC1 | |
| SCHEMBL19846644 | 0.81 | POLB (0.42) | POLBPTPN7DUSP3RXFP1NPC1 | |
| SCHEMBL15817725 | 0.81 | POLB (0.42) | POLBPTPN7DUSP3RXFP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075699-A2 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2011-06-23 | — | — | WO | disclosed |