Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 14/20 | 0.53 |
| ▸ | MC3R | P41968 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | UGCG | Q16739 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MC5R | P33032 | 2/20 | 0.38 |
| ▸ | MC1R | Q01726 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6735971 | 1.00 | MC4R (0.53) | MC4RMC3RCYP3A4UGCGMAPT | |
| SCHEMBL6736762 | 0.94 | MC4R (0.59) | MC4RMC3RCYP3A4UGCGMAPT | |
| SCHEMBL6736763 | 0.94 | MC4R (0.59) | MC4RMC3RCYP3A4UGCGMAPT | |
| SCHEMBL6736765 | 0.94 | MC4R (0.59) | MC4RMC3RCYP3A4UGCGMAPT | |
| SCHEMBL6737704 | 0.91 | MC4R (0.50) | MC4RMC3RCYP3A4UGCGMAPT | |
| SCHEMBL6739684 | 0.84 | MC4R (0.60) | MC4RMC3RCYP3A4UGCGALDH1A1 | |
| SCHEMBL6739689 | 0.84 | MC4R (0.60) | MC4RMC3RCYP3A4UGCGALDH1A1 | |
| SCHEMBL6739687 | 0.84 | MC4R (0.60) | MC4RMC3RCYP3A4UGCGALDH1A1 | |
| SCHEMBL6738398 | 0.83 | MC4R (0.58) | MC4RMC3RCYP3A4UGCGALDH1A1 | |
| SCHEMBL6738395 | 0.83 | MC4R (0.58) | MC4RMC3RCYP3A4UGCGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058735-A2 | LIGANDS OF MELANOCORTIN RECEPTORS AND COMPOSITIONS AND METHODS RELATED THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2004-07-15 | — | — | WO | disclosed |