Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 19/20 | 0.73 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL937272 | 0.87 | PRKD1 (0.77) | PRKD1 | |
| SCHEMBL1053880 | 0.86 | PRKD1 (0.76) | PRKD1 | |
| SCHEMBL1083327 | 0.85 | PRKD1 (1.00) | PRKD1 | |
| SCHEMBL6923674 | 0.85 | PRKD1 (0.78) | PRKD1RAF1BRAF | |
| SCHEMBL6924033 | 0.79 | PRKD1 (0.64) | PRKD1 | |
| SCHEMBL1083601 | 0.78 | PRKD1 (0.81) | PRKD1 | |
| SCHEMBL6923111 | 0.77 | PRKD1 (1.00) | PRKD1 | |
| SCHEMBL937926 | 0.77 | PRKD1 (0.83) | PRKD1 | |
| SCHEMBL6924257 | 0.77 | PRKD1 (0.83) | PRKD1 | |
| SCHEMBL6922426 | 0.77 | PRKD1 (0.82) | PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009484-A1 | ARYLPYRAZOLES AND ARYLISOXAZOLES AND THEIR USE AS PKD MODULATORS | NOVARTIS AG (CH) | 2011-01-27 | — | — | WO | disclosed |