Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.70 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.51 |
| ▸ | CTRC | Q99895 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923344 | 0.89 | F2 (0.72) | F2PRSS2CTRC | |
| SCHEMBL7645126 | 0.83 | F2 (1.00) | F2 | |
| SCHEMBL7645122 | 0.82 | F2 (0.71) | F2PRSS2CTRC | |
| Hydrochloric Acid SCHEMBL6749264 | 0.82 | F2 (0.98) | F2 | |
| Hydrochloric Acid SCHEMBL6749262 | 0.81 | F2 (0.70) | F2PRSS2CTRC | |
| SCHEMBL3642375 | 0.79 | F2 (0.55) | F2PRSS2CTRC | |
| SCHEMBL3642393 | 0.78 | F2 (0.54) | F2PRSS2CTRC | |
| SCHEMBL8160877 | 0.77 | F2 (0.54) | F2PRSS2CTRC | |
| SCHEMBL3639421 | 0.77 | F2 (0.53) | F2PRSS2CTRC | |
| SCHEMBL5673644 | 0.77 | F2 (0.70) | F2PRSS2CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518310-B2 | Non-peptidic; inhibits trypsin-like protease, thrombin and embolus formation; anticoagulant | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-02-11 | — | — | US | disclosed |
| EP-0944590-B1 | AMINOGUANIDINES AND ALKOXYGUANIDINES AS PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2002-03-20 | — | — | EP | disclosed |