SCHEMBL692375

SCHEMBL692375

CC=CC(=O)OCCC[Si](C)(C)Cl

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.46
HCAR2 Q8TDS4 4/20 0.41
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TSHR P16473 2/20 0.35
HPGD P15428 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34
GSTP1 P09211 1/20 0.33
APP P05067 5/20 0.31
PRKCA P17252 2/20 0.30
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26094052 0.95 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26094528 0.93 HCAR2 (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26095141 0.93 HCAR2 (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26095278 0.93 HCAR2 (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL22367600 0.93 HCAR2 (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26095543 0.93 HCAR2 (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26092613 0.93 HCAR2 (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26095586 0.93 HCAR2 (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26093415 0.93 HCAR2 (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL26092971 0.93 HCAR2 (0.44) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 964 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240409563-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. 2024-12-12 US claimed
EP-4448536-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. (US) 2024-10-23 EP claimed
CN-116574124-A Method for preparing 3-methacryloxypropyl dimethyl chlorosilane by using microchannel reactor 华诺森(武汉)生物医药技术有限公司 2023-08-11 CN claimed
WO-2023113779-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. (US) 2023-06-22 WO claimed
US-20230183273-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. 2023-06-15 US claimed
US-11597789-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2023-03-07 US claimed
CN-115298535-A Detectable arrays for distinguishing analytes and diagnostics and methods and systems related thereto 恩拓普斯有限公司 2022-11-04 CN claimed
US-20220244250-A1 DETECTABLE ARRAYS, SYSTEMS FOR DIAGNOSIS, AND METHODS OF MAKING AND USING THE SAME ENTOPSIS, INC. 2022-08-04 US claimed
US-20220064381-A1 SILICONE POTTING COMPOSITION AND USES THEREOF ILLINOIS TOOL WORKS INC. (US) 2022-03-03 US claimed
US-11092574-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2021-08-17 US claimed
US-5914418-A MIXING WITH AMMONIUM, PHOSPHONIUM, OXONIUM, SULFONIUM, HALOGENONIUM OR METAL SALTS OF 2,6-DI-TERT-BUTYL-4-HYDROXYMETHYLPHENOL; STORAGE STABILITY DOW CORNING TORAY SILICONE CO., LTD. (JP) 1999-06-22 US claimed
WO-1999020227-A1 PROTECTIVE VARNISH FOR DENTIN DENTSPLY INTERNATIONAL INC. (US) 1999-04-29 WO claimed
WO-1999017716-A2 DENTAL MATERIALS HAVING A NANOSCALE FILLER DENTSPLY INTERNATIONAL INC. (US) 1999-04-15 WO claimed
US-5811565-A TREATING MIXTURE WITH LEWIS ACID HALIDE DOW CORNING TORAY SILICONE CO., LTD. (JP) 1998-09-22 US claimed
EP-0814108-A1 Silyl-linked polyamidoamines and their preparation HERCULES INCORPORATED (US) 1997-12-29 EP claimed
EP-0803507-A2 Polymerization inhibitor for acrylic-functional organo-silicon compounds Dow Corning Toray Silicone Company Limited (JP) 1997-10-29 EP claimed
EP-0593297-B1 Resin composition for coating and paint HITACHI CHEMICAL CO LTD (JP) 1997-04-16 EP claimed
US-5539051-A ACRYLATE RESIN AND ADDITION TYPE RESIN WITH PENDANT SILICON CONTAINING GROUPS, FOR CONCRETE, MASONRY, NONSTAINING HITACHI CHEMICAL COMPANY CO., LTD. (JP) 1996-07-23 US claimed
EP-0593297-A1 Resin composition for coating and paint HITACHI CHEMICAL CO., LTD. (JP) 1994-04-20 EP claimed
US-5190828-A Low-gloss polyacetal resin compositions and molded articles POLYPLASTICS CO., LTD. (JP) 1993-03-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409563-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME SSRP1, RPLP2, RPLP1 ATM 1387/4885HCAR2 1011/4885MAPT 3928/4885
US-20230183273-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME SSRP1, RPLP2, RPLP1 ATM 1387/4885HCAR2 1011/4885MAPT 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.