Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TTR | P02766 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 1/20 | 0.51 |
| ▸ | P4HB | P07237 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2165506 | 1.00 | UNG (0.63) | UNGKMT2ATTRMAPTNSD2 | |
| SCHEMBL935785 | 1.00 | UNG (0.63) | UNGKMT2ATTRMAPTNSD2 | |
| SCHEMBL8230316 | 0.83 | PARP1 (0.50) | UNGKMT2AMAPTPOLBMAPK1 | |
| SCHEMBL4106983 | 0.83 | UNG (0.61) | UNGTTRFBP1P4HBCA1 | |
| SCHEMBL12581543 | 0.80 | UNG (0.58) | UNGKMT2ATTRMAPTPOLB | |
| SCHEMBL8899992 | 0.79 | TTR (0.79) | UNGTTRHSD17B10FBP1P4HB | |
| SCHEMBL808972 | 0.79 | TTR (0.79) | UNGTTRHSD17B10FBP1P4HB | |
| SCHEMBL9075299 | 0.79 | TTR (0.79) | UNGTTRHSD17B10FBP1P4HB | |
| SCHEMBL31490527 | 0.79 | KMT2A (0.63) | UNGKMT2ATTRMAPTNSD2 | |
| SCHEMBL27604259 | 0.79 | UNG (0.73) | UNGTTRHSD17B10TDP1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023077070-A1 | RXFP1 AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-05-04 | — | — | WO | disclosed |
| CN-114380762-A | Isoxazoline hydrazide derivative and preparation method and application thereof | 贵州大学 | 2022-04-22 | — | — | CN | disclosed |
| WO-2011009484-A1 | ARYLPYRAZOLES AND ARYLISOXAZOLES AND THEIR USE AS PKD MODULATORS | NOVARTIS AG (CH) | 2011-01-27 | — | — | WO | disclosed |