Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.80 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.71 |
| ▸ | IGF1R | P08069 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.59 |
| ▸ | PIM1 | P11309 | 2/20 | 0.59 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923861 | 1.00 | CNR1 (0.80) | CNR1ADAMTS5IGF1RHPGDMMP13 | |
| SCHEMBL6929714 | 0.90 | HPGD (0.72) | CNR1ADAMTS5IGF1RHPGDPIM1 | |
| SCHEMBL6929711 | 0.90 | HPGD (0.72) | CNR1ADAMTS5IGF1RHPGDPIM1 | |
| SCHEMBL1248799 | 0.85 | CNR1 (0.81) | CNR1ADAMTS5IGF1RHPGDMMP13 | |
| SCHEMBL1248797 | 0.85 | CNR1 (0.81) | CNR1ADAMTS5IGF1RHPGDMMP13 | |
| SCHEMBL9433307 | 0.85 | CNR1 (0.81) | CNR1ADAMTS5IGF1RHPGDMMP13 | |
| SCHEMBL7066328 | 0.84 | HPGD (0.67) | CNR1ADAMTS5IGF1RHPGDPTPN1 | |
| SCHEMBL7066323 | 0.84 | HPGD (0.67) | CNR1ADAMTS5IGF1RHPGDPTPN1 | |
| SCHEMBL8159449 | 0.83 | HPGD (0.81) | CNR1ADAMTS5IGF1RHPGDMMP13 | |
| SCHEMBL8159450 | 0.83 | HPGD (0.81) | CNR1ADAMTS5IGF1RHPGDMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518268-B1 | Telomerase inhibitors and methods of their use | GERON CORPORATION | 2003-02-11 | — | — | US | claimed |
| WO-2001002377-A9 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORP (US) | 2001-10-11 | — | — | WO | claimed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | claimed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | claimed |
| US-6518268-B1 | Telomerase inhibitors and methods of their use | GERON CORPORATION | 2003-02-11 | — | — | US | disclosed |
| WO-2001002377-A9 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORP (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |