SCHEMBL6924024

SCHEMBL6924024

[SiH3]O[SiH3].c1ccc2c(c1)-c1ccccc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
MAPK1 P28482 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
NPC1 O15118 2/20 0.47
MAOA P21397 2/20 0.47
KDM4E B2RXH2 2/20 0.47
LMNA P02545 2/20 0.47
POLB P06746 2/20 0.47
MAPT P10636 2/20 0.47
S100A4 P26447 2/20 0.47
RAB9A P51151 2/20 0.47
BLM P54132 2/20 0.47
APAF1 O14727 2/20 0.47
TDP2 O95551 2/20 0.47
CES2 O00748 1/20 0.47
TERT O14746 1/20 0.47
PLIN1 O60240 1/20 0.47
S1PR4 O95977 1/20 0.47
PLA2G1B P04054 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28694051 0.82 MEN1 (0.61) MEN1KMT2AMAPK1SMN1; SMN2NPC1
SCHEMBL29711875 0.82 MEN1 (0.61) MEN1KMT2AMAPK1SMN1; SMN2NPC1
SCHEMBL28904690 0.82 MEN1 (0.61) MEN1KMT2AMAPK1SMN1; SMN2NPC1
SCHEMBL4368339 0.82 MEN1 (0.61) MEN1KMT2AMAPK1SMN1; SMN2NPC1
SCHEMBL58152 0.82 MEN1 (0.61) MEN1KMT2AMAPK1SMN1; SMN2NPC1
SCHEMBL29437946 0.82 MEN1 (0.61) MEN1KMT2AMAPK1SMN1; SMN2NPC1
SCHEMBL29543474 0.82 MEN1 (0.61) MEN1KMT2AMAPK1SMN1; SMN2NPC1
SCHEMBL49870 0.82 MEN1 (0.61) MEN1KMT2AMAPK1SMN1; SMN2NPC1
SCHEMBL11875421 0.82 MEN1 (0.61) MEN1KMT2AMAPK1SMN1; SMN2NPC1
SCHEMBL29067593 0.82 MEN1 (0.61) MEN1KMT2AMAPK1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030109128-A1 Semiconductor device and method of manufacturing the same NEC CORPORATION 2003-06-12 US claimed
US-6518170-B2 Multilayer dielectric NEC CORPORATION (JP) 2003-02-11 US claimed
US-20020013046-A1 Semiconductor device and method of manufacturing the same NEC CORPORATION 2002-01-31 US claimed
US-20030109128-A1 Semiconductor device and method of manufacturing the same NEC CORPORATION 2003-06-12 US disclosed
US-6518170-B2 Multilayer dielectric NEC CORPORATION (JP) 2003-02-11 US disclosed
US-20020013046-A1 Semiconductor device and method of manufacturing the same NEC CORPORATION 2002-01-31 US disclosed