SCHEMBL6924265

SCHEMBL6924265

CSc1ccc(-c2cc(Cl)sc2S(=O)(=O)Nc2ccc(C(F)(F)F)c(O[C@@H]3CCN(C)C3)c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6828980 0.92 UTS2R (0.57) UTS2R
SCHEMBL6828976 0.92 UTS2R (0.57) UTS2R
SCHEMBL6828490 0.91 UTS2R (0.57) UTS2R
SCHEMBL6828488 0.91 UTS2R (0.57) UTS2R
SCHEMBL8341637 0.91 UTS2R (0.57) UTS2R
SCHEMBL6826025 0.90 UTS2R (0.59) UTS2R
SCHEMBL6826023 0.90 UTS2R (0.59) UTS2R
SCHEMBL6828624 0.89 UTS2R (0.55) UTS2R
SCHEMBL6828626 0.89 UTS2R (0.55) UTS2R
SCHEMBL6828382 0.89 UTS2R (0.56) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043368-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO claimed