Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 5/20 | 0.45 |
| ▸ | HTR2C | P28335 | 5/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.45 |
| ▸ | DRD1 | P21728 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12515684 | 1.00 | HRH2 (0.46) | HRH2HTR2AHTR2CADRA2ADRD2 | |
| SCHEMBL6923270 | 1.00 | HRH2 (0.46) | HRH2HTR2AHTR2CADRA2ADRD2 | |
| SCHEMBL19256099 | 1.00 | HRH2 (0.46) | HRH2HTR2AHTR2CADRA2ADRD2 | |
| SCHEMBL12413678 | 1.00 | HRH2 (0.46) | HRH2HTR2AHTR2CADRA2ADRD2 | |
| SCHEMBL12413650 | 1.00 | HRH2 (0.46) | HRH2HTR2AHTR2CADRA2ADRD2 | |
| SCHEMBL12516915 | 1.00 | HRH2 (0.46) | HRH2HTR2AHTR2CADRA2ADRD2 | |
| SCHEMBL12516914 | 1.00 | HRH2 (0.46) | HRH2HTR2AHTR2CADRA2ADRD2 | |
| SCHEMBL12413673 | 1.00 | HRH2 (0.46) | HRH2HTR2AHTR2CADRA2ADRD2 | |
| SCHEMBL19256739 | 1.00 | HRH2 (0.46) | HRH2HTR2AHTR2CADRA2ADRD2 | |
| SCHEMBL12413682 | 1.00 | HRH2 (0.46) | HRH2HTR2AHTR2CADRA2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084846-A1 | QUATERNARY AMMONIUM SALT PRODRUGS | ALKERMES, INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011084851-A1 | ASENAPINE PRODURUGS | ALKERMES, INC. (US) | 2011-07-14 | — | — | WO | disclosed |