Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28204578 | 0.88 | KMT2A (0.58) | MEN1KMT2AEPHX2TDP1KDM4E | |
| SCHEMBL1904207 | 0.85 | HTT (0.66) | MEN1KMT2APOLBHTTHDAC3 | |
| SCHEMBL27404387 | 0.83 | HTT (0.64) | MEN1KMT2AEPHX2HTTSIRT2 | |
| SCHEMBL7094107 | 0.83 | EPHX2 (0.62) | MEN1KMT2AEPHX2HTTSIRT2 | |
| SCHEMBL26357994 | 0.83 | CA12 (0.58) | KMT2APOLBHTTALDH1A1L3MBTL1 | |
| SCHEMBL28634272 | 0.81 | HTT (0.60) | POLBKDM4EHTTALDH1A1MAPK1 | |
| SCHEMBL9164909 | 0.81 | MEN1 (0.54) | MEN1KMT2AEPHX2POLBALDH1A1 | |
| SCHEMBL21814592 | 0.81 | MEN1 (0.47) | MEN1KMT2APOLBHTTHDAC3 | |
| SCHEMBL2295789 | 0.80 | CA12 (0.66) | KMT2APOLBTDP1HTTALDH1A1 | |
| SCHEMBL7385160 | 0.80 | HTT (0.76) | MEN1KMT2AHTTHDAC3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107082747-A | Conveyed for targeted drug and strengthen the compound of siRNA activity | 日东电工株式会社 | 2017-08-22 | — | — | CN | disclosed |
| CN-107043334-A | Conveyed for targeted drug and strengthen the compound of siRNA activity | 日东电工株式会社 | 2017-08-15 | — | — | CN | disclosed |
| WO-2003099810-A2 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |
| EP-1347784-A2 | SIMULTANEOUS DUAL ISOTOPE IMAGING OF CARDIAC PERFUSION AND CARDIAC INFLAMMATION | Bristol-Myers Squibb Pharma Company (US) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002036173-A2 | SIMULTANEOUS DUAL ISOTOPE IMAGING OF CARDIAC PERFUSION AND CARDIAC INFLAMMATION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-05-10 | — | — | WO | disclosed |
| EP-0999856-A2 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION | Du Pont Pharmaceuticals Company (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1998015295-A2 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION | DUPONT PHARMACEUTICALS COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |