Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1173143 | 0.88 | BACE1 (0.56) | BACE1BACE2 | |
| SCHEMBL1173242 | 0.84 | BACE1 (0.59) | BACE1BACE2 | |
| SCHEMBL1172985 | 0.82 | BACE1 (0.67) | BACE1BACE2 | |
| SCHEMBL1173170 | 0.81 | BACE1 (0.79) | BACE1BACE2 | |
| SCHEMBL6924752 | 0.81 | BACE1 (0.69) | BACE1BACE2 | |
| SCHEMBL8216268 | 0.78 | BACE1 (0.52) | BACE1BACE2 | |
| SCHEMBL8216270 | 0.76 | BACE1 (0.57) | BACE1BACE2 | |
| SCHEMBL568171 | 0.75 | BACE2 (0.73) | BACE1BACE2 | |
| SCHEMBL568172 | 0.75 | BACE2 (0.73) | BACE1BACE2 | |
| SCHEMBL2592188 | 0.75 | BACE1 (0.78) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020806-A1 | 3-AMINO-5-PHENYL-5,6-DIHYDRO-2H-[1,4]OXAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-02-24 | — | — | WO | disclosed |