Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 19/20 | 0.70 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.69 |
| ▸ | HRH1 | P35367 | 1/20 | 0.69 |
| ▸ | SYK | P43405 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16599151 | 0.83 | HRH4 (0.52) | HRH4HRH3HRH1 | |
| SCHEMBL601515 | 0.83 | HRH4 (1.00) | HRH4HRH3HRH1 | |
| SCHEMBL6130834 | 0.83 | HRH4 (1.00) | HRH4HRH3HRH1 | |
| SCHEMBL604107 | 0.82 | HRH4 (1.00) | HRH4HRH3HRH1 | |
| SCHEMBL603452 | 0.82 | HRH4 (1.00) | HRH4HRH3HRH1 | |
| SCHEMBL6141960 | 0.82 | HRH4 (1.00) | HRH4HRH3HRH1 | |
| Jnj-7777120 SCHEMBL186434 | 0.82 | HRH4 (1.00) | HRH4HRH3HRH1 | |
| Jnj-7777120 SCHEMBL29381532 | 0.82 | HRH4 (1.00) | HRH4HRH3HRH1 | |
| SCHEMBL6830038 | 0.81 | HRH4 (0.72) | HRH4HRH3HRH1 | |
| SCHEMBL604932 | 0.80 | HRH4 (1.00) | HRH4HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |