SCHEMBL6925901

SCHEMBL6925901

O=C(Cl)c1ccc2c(c1)-c1ccc(C(=O)Cl)cc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 4/20 0.47
S100A4 P26447 1/20 0.45
ALDH1A1 P00352 4/20 0.41
TSHR P16473 4/20 0.41
TTR P02766 2/20 0.39
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.35
HTR7 P34969 1/20 0.35
HTR2B P41595 1/20 0.35
TP53 P04637 1/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
SRD5A1 P18405 1/20 0.34
SRD5A2 P31213 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5667639 1.00 PTPRC (0.47) PTPRCS100A4ALDH1A1TSHRTTR
SCHEMBL6638005 0.93 PTPRC (0.57) PTPRCS100A4ALDH1A1TSHRTTR
SCHEMBL11733475 0.88 TTR (0.53) PTPRCS100A4ALDH1A1TTRNPC1
SCHEMBL7551130 0.85 PTPRC (0.65) PTPRCS100A4ALDH1A1TTRNPC1
SCHEMBL28399814 0.83 TTR (0.59) PTPRCS100A4ALDH1A1TTRNPC1
SCHEMBL28397117 0.83 TTR (0.59) PTPRCS100A4ALDH1A1TTRNPC1
Diphenylether SCHEMBL11499272 0.82 PARP10 (0.50) PTPRCS100A4TSHRTTRSMN1; SMN2
SCHEMBL3300661 0.81 TTR (0.67) PTPRCS100A4ALDH1A1TSHRTTR
SCHEMBL13139835 0.80 CYP2C8 (0.39) PTPRCALDH1A1TSHRTTRNPC1
SCHEMBL9812968 0.80 TSHR (0.46) ALDH1A1TSHRTTRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed
US-4197393-A Biphenylene polymers and resins and the production thereof UNIVERSITY PATENTS, INC. (US) 1980-04-08 US disclosed