Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8231829 | 1.00 | TACR1 (0.74) | TACR1 | |
| SCHEMBL6922756 | 0.84 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6922765 | 0.80 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7573137 | 0.79 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7796972 | 0.79 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7797004 | 0.79 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6922771 | 0.79 | TACR1 (0.73) | TACR1 | |
| SCHEMBL8520649 | 0.78 | TACR1 (0.95) | TACR1 | |
| SCHEMBL6924338 | 0.77 | TACR1 (0.75) | TACR1 | |
| SCHEMBL7797010 | 0.77 | TACR1 (0.79) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518273-B1 | 2-aryl indole derivative as antagonists of tachykinins | MERCK SHARP & DOHME LTD. | 2003-02-11 | — | — | US | disclosed |
| WO-2000051984-A1 | 2-ARYL INDOLE DERIVATIVES AS ANTAGONISTS OF TACHYKININS | MERCK SHARP & DOHME LIMITED (GB) | 2000-09-08 | — | — | WO | disclosed |