Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6923631 | 0.92 | TACR1 (0.85) | TACR1LMNA | |
| SCHEMBL6928003 | 0.90 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7571859 | 0.88 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6925242 | 0.82 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6922478 | 0.80 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6926943 | 0.78 | TACR1 (0.82) | TACR1 | |
| SCHEMBL6926601 | 0.75 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7668094 | 0.74 | TACR1 (0.63) | TACR1LMNA | |
| SCHEMBL6929085 | 0.71 | TACR1 (0.59) | TACR1 | |
| SCHEMBL6928547 | 0.71 | TACR1 (0.82) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518273-B1 | 2-aryl indole derivative as antagonists of tachykinins | MERCK SHARP & DOHME LTD. | 2003-02-11 | — | — | US | disclosed |
| WO-2000051984-A1 | 2-ARYL INDOLE DERIVATIVES AS ANTAGONISTS OF TACHYKININS | MERCK SHARP & DOHME LIMITED (GB) | 2000-09-08 | — | — | WO | disclosed |