Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926561 | 0.90 | TACR1 (0.65) | TACR1TBXAS1 | |
| Hydrochloric Acid SCHEMBL7790354 | 0.89 | TACR1 (0.64) | TACR1TBXAS1 | |
| SCHEMBL7790361 | 0.86 | TACR1 (0.61) | TACR1 | |
| SCHEMBL6924338 | 0.81 | TACR1 (0.75) | TACR1 | |
| SCHEMBL7790320 | 0.81 | TACR1 (0.54) | TACR1TBXAS1 | |
| SCHEMBL7797019 | 0.80 | TACR1 (0.55) | TACR1TBXAS1 | |
| Hydrochloric Acid SCHEMBL7798859 | 0.79 | TACR1 (0.53) | TACR1TBXAS1 | |
| SCHEMBL7798879 | 0.78 | TACR1 (0.52) | TACR1TBXAS1 | |
| SCHEMBL7797108 | 0.78 | TACR1 (0.57) | TACR1 | |
| SCHEMBL7797105 | 0.78 | TACR1 (0.57) | TACR1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518273-B1 | 2-aryl indole derivative as antagonists of tachykinins | MERCK SHARP & DOHME LTD. | 2003-02-11 | — | — | US | disclosed |
| WO-2000051984-A1 | 2-ARYL INDOLE DERIVATIVES AS ANTAGONISTS OF TACHYKININS | MERCK SHARP & DOHME LIMITED (GB) | 2000-09-08 | — | — | WO | disclosed |