Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 3/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13835895 | 0.78 | KDM4E (0.41) | ALDH1A1SMN1; SMN2RXFP1KDM4EMAPT | |
| SCHEMBL10862608 | 0.77 | KDM4E (0.40) | ALDH1A1SMN1; SMN2RXFP1KDM4EMAPT | |
| SCHEMBL27835870 | 0.76 | DHODH (0.33) | ALDH1A1SMN1; SMN2KDM4EKMT2ALIPE | |
| SCHEMBL4826668 | 0.74 | POLB (0.53) | ALDH1A1SMN1; SMN2RXFP1KDM4EMAPT | |
| SCHEMBL1003996 | 0.73 | POLB (0.52) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL27579609 | 0.72 | CNR1 (0.35) | KDM4EMAPTMEN1KMT2ALIPE | |
| SCHEMBL13835897 | 0.72 | KDM4E (0.37) | ALDH1A1SMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL17323560 | 0.72 | DHODH (0.36) | SMN1; SMN2KDM4EKMT2ALIPETAS1R3 | |
| SCHEMBL7406703 | 0.71 | POLB (0.50) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL1004648 | 0.71 | POLB (0.55) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | claimed |