Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.36 |
| ▸ | F10 | P00742 | 5/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.34 |
| ▸ | F12 | P00748 | 3/20 | 0.33 |
| ▸ | F7 | P08709 | 3/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927806 | 0.82 | MAPK8 (0.34) | F2 | |
| SCHEMBL6926517 | 0.79 | F2 (0.49) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6924535 | 0.79 | F2 (0.41) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6924250 | 0.77 | F2 (0.47) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6924463 | 0.77 | F2 (0.36) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6921526 | 0.76 | F2 (0.47) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6924800 | 0.74 | F2 (0.41) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6923244 | 0.73 | F2 (0.46) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6926330 | 0.73 | F2 (0.44) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL17221932 | 0.73 | F2 (0.36) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515011-B2 | Anticoagulants | MERCK & CO., INC. | 2003-02-04 | — | — | US | disclosed |