Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1894769 | 0.90 | MEN1 (0.50) | MEN1KMT2ANPC1PKMALDH1A1 | |
| SCHEMBL1954089 | 0.88 | MEN1 (0.51) | MEN1KMT2ANPC1PKMALDH1A1 | |
| SCHEMBL1952324 | 0.86 | MEN1 (0.48) | MEN1KMT2ANPC1PKMALDH1A1 | |
| SCHEMBL14803205 | 0.84 | MEN1 (0.45) | MEN1KMT2ANPC1PKMALDH1A1 | |
| SCHEMBL2183410 | 0.84 | MEN1 (0.47) | MEN1KMT2ANPC1PKMALDH1A1 | |
| SCHEMBL1895872 | 0.84 | ANO1 (0.52) | MEN1KMT2ANPC1MAPTCASP3 | |
| SCHEMBL1899120 | 0.83 | ANO1 (0.51) | MEN1KMT2AANO1 | |
| SCHEMBL12271012 | 0.82 | MEN1 (0.48) | MEN1KMT2ANPC1PKMALDH1A1 | |
| SCHEMBL2180967 | 0.82 | MEN1 (0.46) | MEN1KMT2ANPC1PKMALDH1A1 | |
| SCHEMBL1953087 | 0.81 | MEN1 (0.55) | MEN1KMT2ANPC1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109551-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-09-09 | — | — | WO | disclosed |