SCHEMBL69291

SCHEMBL69291

Cn1c2ccc(C(=O)O)cc2c2cc(C(=O)O)ccc21

nearest known ligand 0.83

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.83
HPGD P15428 5/20 0.57
ALDH1A1 P00352 3/20 0.57
MAPT P10636 1/20 0.55
HSD17B10 Q99714 1/20 0.55
HCAR3 P49019 7/20 0.51
TBXAS1 P24557 1/20 0.49
HCAR2 Q8TDS4 1/20 0.47
EGFR P00533 1/20 0.45
SRC P12931 1/20 0.45
THRB P10828 1/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
TEAD1 P28347 1/20 0.44
TEAD4 Q15561 1/20 0.44
TEAD2 Q15562 1/20 0.44
TEAD3 Q99594 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30850787 0.91 KDM4E (1.00) KDM4EHPGDALDH1A1MAPTHSD17B10
SCHEMBL3102894 0.91 KDM4E (1.00) KDM4EHPGDALDH1A1MAPTHSD17B10
SCHEMBL1586533 0.83 KDM4E (0.61) KDM4EHPGDALDH1A1MAPTHSD17B10
SCHEMBL28121877 0.83 KDM4E (0.61) KDM4EHPGDALDH1A1MAPTHSD17B10
SCHEMBL6510783 0.82 KDM4E (0.59) KDM4EHPGDALDH1A1HSD17B10HCAR3
SCHEMBL21775981 0.82 KDM4E (0.64) KDM4EHPGDALDH1A1MAPTHSD17B10
SCHEMBL8471293 0.81 KDM4E (0.68) KDM4EHPGDALDH1A1MAPTHSD17B10
SCHEMBL24016497 0.81 KDM4E (0.57) KDM4EHPGDALDH1A1MAPTHSD17B10
SCHEMBL24016050 0.81 TEAD1 (0.61) KDM4EHPGDALDH1A1MAPTHSD17B10
SCHEMBL2482759 0.80 KDM4E (0.81) KDM4EHPGDALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105523992-A General synthetic method for N-substituted carbazole dicarboxylic acid derivatives SHANGHAI MASHILABS (CHEMICAL) CO LTD 2016-04-27 CN claimed
US-20160248025-A1 Organic Electroluminescent Device UDC IRELAND LTD (IE) 2016-08-25 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-0617337-B1 Toner for developing electrostatic image TOMOEGAWA PAPER CO LTD (JP) 2000-07-12 EP disclosed
US-6054242-A BINDER, COLORANT AND CARBODIIMIDE-CROSSLINKED POLYESTER BASED ON THE REACTION OF A POLYESTER WITH A POLYCARBODIIMIDE RESIN HAVING A CARBODIIMIDE GROUP-N=C=N-, AND A LOW MELTING POINT COMPOUND; OFFSET RESISTANCE, SHELFLIFE TOMOGAWA PAPER CO., LTD. (JP) 2000-04-25 US disclosed
EP-0655656-B1 Toner for developing electrostatic image TOMOEGAWA PAPER CO LTD (JP) 2000-03-15 EP disclosed
US-5902709-A BRANCHED POLYESTER HAVING SPECIFIED TETRAHYDROFURAN-INSOUBLE CONTENT, MOLECULAR WEIGHT DISTRIBUTION TOMOEGAWA PAPER CO., LTD. (JP) 1999-05-11 US disclosed
US-5830979-A LOW MOLECULAR WEIGHT, POLYCARBOXYLIC ACID OR POLYALCOHOL HAVING AT LEAST 3 GROUPS TOMOEGAWA PAPER CO., LTD. (JP) 1998-11-03 US disclosed
US-5565292-A LOW TEMPERATURE FIRING; BLEND OF COLORANT AND MODIFIED POLYESTER TOMOEGAWA PAPER CO., LTD. (JP) 1996-10-15 US disclosed
US-5466553-A Phenolic hydroxyl group-containing polyester binder resin TOMOEGAWA PAPER CO., LTD. (JP) 1995-11-14 US disclosed
US-5447814-A Electrostatic images with low temperature fixing properties TOMOEGAWA PAPER CO., LTD. (JP) 1995-09-05 US disclosed
EP-0655656-A1 Toner for developing electrostatic image TOMOEGAWA PAPER CO. LTD. (JP) 1995-05-31 EP disclosed
EP-0617337-A2 Toner for developing electrostatic image TOMOEGAWA PAPER CO. LTD. (JP) 1994-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 KDM4E 717/4885HPGD 3275/4885ALDH1A1 1882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.