Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 5/20 | 0.39 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105374 | 0.84 | HTR2A (0.47) | HTR2AHRH1KDM4EHSD17B10LMNA | |
| SCHEMBL1453437 | 0.80 | HTR2A (0.42) | HTR2AHRH1KDM4EHSD17B10LMNA | |
| SCHEMBL4005225 | 0.78 | HTR2A (0.41) | HTR2AHRH1KDM4EHSD17B10LMNA | |
| SCHEMBL11127960 | 0.76 | KDM4E (0.41) | HTR2AHRH1KDM4EHSD17B10LMNA | |
| SCHEMBL1454082 | 0.76 | HTR2A (0.44) | HTR2AHRH1KDM4EHSD17B10LMNA | |
| SCHEMBL7783135 | 0.75 | HTR2A (0.39) | HTR2AHRH1KDM4EHSD17B10LMNA | |
| SCHEMBL1452870 | 0.73 | HTR2A (0.42) | HTR2AHRH1KDM4EHSD17B10LMNA | |
| SCHEMBL23548026 | 0.72 | EGFR (0.55) | EGFRSRCHTR2AHRH1KDM4E | |
| SCHEMBL8861732 | 0.71 | HTR2A (0.51) | HTR2AHRH1KDM4EHSD17B10LMNA | |
| SCHEMBL6238627 | 0.71 | HTR2A (0.41) | HTR2AHRH1KDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980375-A4 | SILYLATED AND N-SILYLATED COMPOUND SYNTHESIS | BOULDER SCIENT CO (US) | 2003-01-22 | — | — | EP | disclosed |
| EP-0980375-A1 | N-SILYLATED COMPOUND SYNTHESIS | BOULDER SCIENTIFIC COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1999038871-A1 | SILYLATED AND N-SILYLATED COMPOUND SYNTHESIS | BOULDER SCIENTIFIC COMPANY (US) | 1999-08-05 | — | — | WO | disclosed |