Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | CDC25B | P30305 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29459734 | 0.98 | NR4A1 (0.63) | NR4A1NR4A2NR4A3KMT2APOLB | |
| SCHEMBL137605 | 0.98 | NR4A1 (0.63) | NR4A1NR4A2NR4A3KMT2APOLB | |
| SCHEMBL29262289 | 0.96 | NR4A1 (0.61) | NR4A1NR4A2NR4A3KMT2APOLB | |
| SCHEMBL11422834 | 0.96 | NR4A1 (0.61) | NR4A1NR4A2NR4A3KMT2APOLB | |
| SCHEMBL14672373 | 0.96 | NR4A1 (0.61) | NR4A1NR4A2NR4A3KMT2APOLB | |
| Ethylene SCHEMBL10012407 | 0.94 | NR4A1 (0.59) | NR4A1NR4A2NR4A3KMT2APOLB | |
| Hydrazine SCHEMBL28964205 | 0.94 | NR4A1 (0.59) | NR4A1NR4A2NR4A3KMT2APOLB | |
| SCHEMBL10627190 | 0.89 | NR4A1 (0.69) | NR4A1NR4A2NR4A3KMT2APOLB | |
| SCHEMBL9472404 | 0.89 | NR4A1 (0.58) | NR4A1NR4A2NR4A3KMT2APOLB | |
| Propene SCHEMBL10012775 | 0.87 | NR4A1 (0.52) | NR4A1NR4A2NR4A3KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051655-A4 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-1051655-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | Ista Pharmaceuticals, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999039238-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | KERATOFORM, INC. (US) | 1999-08-05 | — | — | WO | disclosed |