Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | USP19 | O94966 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930208 | 0.80 | KDM4E (0.36) | KDM4EALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL6933831 | 0.77 | KDM4E (0.33) | KDM4EALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL6934260 | 0.77 | KDM4E (0.33) | KDM4EALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL6935528 | 0.73 | MAPT (0.41) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL7609898 | 0.68 | POLB (0.34) | KDM4EALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL6928265 | 0.67 | GAA (0.39) | GAA | |
| SCHEMBL7130760 | 0.61 | NPC1 (0.35) | KDM4EALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL15723646 | 0.61 | KDM4E (0.32) | KDM4EALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL6933456 | 0.59 | GAA (0.30) | GAA | |
| SCHEMBL24007323 | 0.58 | KDM4E (0.42) | KDM4EALDH1A1KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | claimed |
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |