Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15366358 | 0.89 | TSHR (0.48) | CA1CA2CA7CA9TSHR | |
| SCHEMBL5694054 | 0.86 | CA1 (0.51) | CA1CA2CA7CA9TSHR | |
| SCHEMBL14747305 | 0.86 | CA1 (0.51) | CA1CA2CA7CA9TSHR | |
| SCHEMBL13841805 | 0.86 | CA1 (0.51) | CA1CA2CA7CA9TSHR | |
| SCHEMBL5742123 | 0.84 | CA1 (0.56) | CA1CA2CA7CA9TSHR | |
| SCHEMBL18591521 | 0.83 | MAPT (0.41) | CA1CA2CA7CA9TSHR | |
| SCHEMBL14372163 | 0.82 | CA1 (0.47) | CA1CA2CA7CA9TSHR | |
| SCHEMBL9838648 | 0.82 | CA1 (0.47) | CA1CA2CA7CA9TSHR | |
| SCHEMBL6549684 | 0.82 | CA1 (0.47) | CA1CA2CA7CA9TSHR | |
| SCHEMBL19390430 | 0.82 | CA1 (0.47) | CA1CA2CA7CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787739-B1 | Anti-adhesive piperidine and pyrollidine -carboxylic acids | GLYCOREX AB (SE) | 2003-01-29 | — | — | EP | disclosed |
| US-5739300-A | Antiadhesive piperidine-and pyrrolidinecarboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| EP-0787739-A1 | Anti-adhesive piperidine and pyrollidine -carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-06 | — | — | EP | disclosed |