Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.64 |
| ▸ | MPC2 | O95563 | 1/20 | 0.63 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12515968 | 0.88 | PPARG (0.71) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL10223581 | 0.87 | PPARG (0.70) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL6931522 | 0.87 | PPARG (0.70) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL6928457 | 0.87 | PPARG (0.70) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL935983 | 0.82 | PPARG (1.00) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL12517394 | 0.82 | PPARG (0.81) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL6928337 | 0.82 | PPARG (1.00) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL6928620 | 0.82 | PPARG (1.00) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL6931666 | 0.82 | PPARG (0.81) | PPARGFFAR1MPC2CYP2C8CYP2C9 | |
| SCHEMBL6929481 | 0.82 | PPARG (1.00) | PPARGFFAR1MPC2CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084456-A1 | PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF DIABETES MELLITUS AND OTHER METABOLIC DISEASES | METABOLIC SOLUTIONS DEVELOPMENT COMPANY (US) | 2011-07-14 | — | — | WO | disclosed |