SCHEMBL6931229

SCHEMBL6931229

CC(C(=O)[O-])C(O)O.CC(C(=O)[O-])C(O)O.CC(C(=O)[O-])C(O)O.[Bi+3]

nearest known ligand 0.56

Known targets — ChEMBL curated mechanism

HRH2

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
CA1 P00915 6/20 0.33
CA4 P22748 3/20 0.33
CA2 P00918 1/20 0.33
LMNA P02545 1/20 0.32
CYP3A4 P08684 2/20 0.32
TSHR P16473 2/20 0.32
NFKB1 P19838 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL29044274 0.94
SCHEMBL6735450 0.76 CA1 (0.40) TP53CA1CA4CA2CYP3A4
L-Lactic Acid SCHEMBL216130 0.76 TP53 (0.50) TP53CA1CA4CA2LMNA
Potassium Ion SCHEMBL11445670 0.76 CA4 (0.44) TP53CA1CA4CA2CYP3A4
Lithium Ion SCHEMBL11445716 0.76 CA1 (0.40) TP53CA1CA4CA2CYP3A4
Silver SCHEMBL6735440 0.76 CA1 (0.40) TP53CA1CA4CA2CYP3A4
L-Lactic Acid SCHEMBL11565753 0.73 TP53 (0.47) TP53CA1CA4CA2LMNA
SCHEMBL15022939 0.71
L-Lactic Acid SCHEMBL17500030 0.69 TP53 (0.50) TP53CA1CA4CA2LMNA
L-Lactic Acid SCHEMBL9764800 0.69 TP53 (0.50) TP53CA1CA4CA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6572972-B2 Mixture of organobismuth compound and epoxy resin binder SOLUTIA AUSTRIA GMBH (AT) 2003-06-03 US disclosed
US-20030021999-A1 Aqueous binders MONCHEM INTERNATIONAL, INC. 2003-01-30 US disclosed