Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515493 | 0.97 | MEN1 (0.31) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL8960554 | 0.97 | MEN1 (0.31) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL8960724 | 0.92 | — | — | |
| SCHEMBL6195024 | 0.80 | — | — | |
| SCHEMBL8960934 | 0.80 | — | — | |
| SCHEMBL8960930 | 0.80 | — | — | |
| SCHEMBL1285182 | 0.79 | TSHR (0.40) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL5142088 | 0.77 | TSHR (0.44) | — | |
| SCHEMBL22807004 | 0.77 | TSHR (0.44) | — | |
| SCHEMBL11375964 | 0.77 | MEN1 (0.35) | MEN1CYP3A4ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370519-A1 | SYNTHETIC EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002068380-A1 | SYNTHETIC EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |
| EP-0693284-A1 | PROSTACYCLIN-CONTAINING OLEAGINOUS OINTMENT | TEIJIN LIMITED (JP) | 1996-01-24 | — | — | EP | disclosed |