Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 14/20 | 0.61 |
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.61 |
| ▸ | PPARG | P37231 | 4/20 | 0.59 |
| ▸ | PPARD | Q03181 | 4/20 | 0.59 |
| ▸ | PPARA | Q07869 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933780 | 0.97 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10675071 | 0.88 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL6934443 | 0.87 | GRM2 (0.70) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL6938792 | 0.87 | PPARG (0.70) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL6939625 | 0.86 | PPARG (0.78) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL6137114 | 0.86 | PPARG (0.75) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9734215 | 0.85 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10732133 | 0.84 | CYSLTR1 (0.60) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10893732 | 0.84 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL6934143 | 0.84 | PPARG (0.74) | CYSLTR2CYSLTR1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | disclosed |