Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899427 | 0.84 | ATM (0.45) | HDAC8MAPTL3MBTL1GAALMNA | |
| SCHEMBL7418674 | 0.83 | KDM4E (0.59) | HDAC8MAPTL3MBTL1GAALMNA | |
| SCHEMBL7418675 | 0.83 | KDM4E (0.59) | HDAC8MAPTL3MBTL1GAALMNA | |
| SCHEMBL6923827 | 0.83 | HDAC8 (0.61) | HDAC8MAPTL3MBTL1GAALMNA | |
| SCHEMBL7924687 | 0.83 | KDM4E (0.59) | HDAC8MAPTL3MBTL1GAALMNA | |
| SCHEMBL10783630 | 0.83 | KDM4E (0.59) | HDAC8MAPTL3MBTL1GAALMNA | |
| SCHEMBL10783627 | 0.83 | KDM4E (0.59) | HDAC8MAPTL3MBTL1GAALMNA | |
| SCHEMBL5995590 | 0.83 | KDM4E (0.59) | HDAC8MAPTL3MBTL1GAALMNA | |
| SCHEMBL6922818 | 0.83 | HDAC8 (0.61) | HDAC8MAPTL3MBTL1GAALMNA | |
| SCHEMBL6922820 | 0.83 | HDAC8 (0.61) | HDAC8MAPTL3MBTL1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286653-A1 | COMPOSITION CONTAINING AT LEAST ONE ARYL OXIME AND AT LEAST ONE ACTIVE SUBSTANCE FOR TREATING ACNE AND THE USE THEREOF | MERCK PATENT GmbH (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001089467-A1 | COMPOSITION CONTAINING AT LEAST ONE ARYL OXIME AND AT LEAST ONE ACTIVE SUBSTANCE FOR TREATING ACNE AND THE USE THEREOF | MERCK PATENT GMBH (DE) | 2001-11-29 | — | — | WO | disclosed |