Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 14/20 | 0.67 |
| ▸ | HTR2B | P41595 | 6/20 | 0.67 |
| ▸ | HRH1 | P35367 | 5/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6462539 | 0.88 | MCHR1 (0.68) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| Hydrochloric Acid SCHEMBL6462525 | 0.88 | MCHR1 (0.68) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6878425 | 0.87 | MCHR1 (0.72) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6878434 | 0.87 | MCHR1 (0.72) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6880804 | 0.83 | MCHR1 (0.84) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6880809 | 0.83 | MCHR1 (0.84) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6464245 | 0.83 | MCHR1 (0.67) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| SCHEMBL6464237 | 0.83 | MCHR1 (0.67) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| Hydrochloric Acid SCHEMBL6455503 | 0.83 | MCHR1 (0.83) | MCHR1ADRA2AHTR2BHRH1ADRA1A | |
| Hydrochloric Acid SCHEMBL6455513 | 0.83 | MCHR1 (0.83) | MCHR1ADRA2AHTR2BHRH1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |