Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.76 |
| ▸ | HSP90AB1 | P08238 | 16/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655535 | 1.00 | HSP90AA1 (0.76) | HSP90AA1HSP90AB1 | |
| SCHEMBL656960 | 0.98 | HSP90AA1 (0.75) | HSP90AA1HSP90AB1 | |
| SCHEMBL694232 | 0.98 | HSP90AA1 (0.75) | HSP90AA1HSP90AB1 | |
| SCHEMBL16354097 | 0.96 | HSP90AA1 (0.71) | HSP90AA1HSP90AB1 | |
| SCHEMBL655450 | 0.91 | HSP90AA1 (0.80) | HSP90AA1HSP90AB1 | |
| SCHEMBL655449 | 0.91 | HSP90AA1 (0.80) | HSP90AA1HSP90AB1 | |
| SCHEMBL16354099 | 0.90 | HSP90AA1 (0.69) | HSP90AA1HSP90AB1 | |
| SCHEMBL658662 | 0.88 | HSP90AA1 (0.81) | HSP90AA1HSP90AB1 | |
| SCHEMBL16354235 | 0.87 | HSP90AA1 (0.81) | HSP90AA1HSP90AB1 | |
| SCHEMBL16354233 | 0.87 | HSP90AA1 (0.81) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993556-B2 | Resorcinol derivatives as HSP90 inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-03-31 | — | — | US | claimed |
| EP-2421833-B1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2015-01-14 | — | — | EP | claimed |
| EP-2421833-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | Nerviano Medical Sciences S.r.l. (IT) | 2012-02-29 | — | — | EP | claimed |
| WO-2010121963-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2010-10-28 | — | — | WO | claimed |
| EP-2421833-B1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2015-01-14 | — | — | EP | disclosed |
| EP-2421833-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | Nerviano Medical Sciences S.r.l. (IT) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010121963-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2010-10-28 | — | — | WO | disclosed |