Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.56 |
| ▸ | PPARA | Q07869 | 10/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936578 | 0.91 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL5209129 | 0.89 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL5208194 | 0.89 | PPARD (0.55) | PPARGPPARAPPARD | |
| SCHEMBL6933038 | 0.88 | PPARD (0.61) | PPARGPPARAPPARD | |
| SCHEMBL6932822 | 0.88 | PPARD (0.56) | PPARGPPARAPPARD | |
| SCHEMBL6936579 | 0.87 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL6936964 | 0.86 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL6936573 | 0.84 | PPARG (0.52) | PPARGPPARAPPARD | |
| SCHEMBL5205576 | 0.83 | PPARG (0.53) | PPARGPPARAPPARD | |
| SCHEMBL6936584 | 0.82 | PLA2G4B (0.59) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | claimed |
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | claimed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | claimed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | claimed |
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | disclosed |
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | disclosed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |