Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 4/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136150 | 0.85 | KDM4E (0.39) | KDM4EPIK3CDTSHRNAAA | |
| SCHEMBL1056664 | 0.78 | KDM4E (0.46) | KDM4EPIK3CDNAAA | |
| SCHEMBL6551930 | 0.77 | KDM4E (0.43) | KDM4EPIK3CDNAAA | |
| SCHEMBL27739324 | 0.77 | SMN1; SMN2 (0.34) | TSHR | |
| SCHEMBL12878433 | 0.77 | KDM4E (0.45) | KDM4EPIK3CDNAAAFAAH | |
| SCHEMBL10732707 | 0.77 | KDM4E (0.45) | KDM4EPIK3CDNAAA | |
| SCHEMBL4194412 | 0.75 | KDM4E (0.40) | KDM4EPIK3CDNAAAFAAH | |
| SCHEMBL7136148 | 0.74 | KDM4E (0.38) | KDM4EPIK3CDNAAA | |
| SCHEMBL8865227 | 0.74 | KDM4E (0.43) | KDM4EPIK3CDNAAA | |
| SCHEMBL16044897 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101287738-B | Imidazo benzodiazepine derivatives | HOFFMANN LA ROCHE | 2011-08-10 | — | — | CN | disclosed |
| CN-101287738-A | Imidazo benzodiazepine derivatives | HOFFMANN LA ROCHE (CH) | 2008-10-15 | — | — | CN | disclosed |
| EP-0703219-B2 | Method for the preparation of an N-vinyl compound | JAPAN VAM & POVAL CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| EP-0703219-B1 | Method for the preparation of an N-vinyl compound | SHIN ETSU VINYL (JP) | 2000-09-20 | — | — | EP | disclosed |
| EP-0699664-B1 | N-(aLpha-acyloxyethyl) compound and method for the preparation thereof | SHIN ETSU VINYL ACETATE CO LTD (JP) | 1998-09-23 | — | — | EP | disclosed |
| US-5708167-A | FORMING A VINYL GROUP BY REMOVAL OF ACYLOXY GROUP FROM ETHYL ON HETERO RING | SHIN-ETSU VINYL ACETATE CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| US-5608057-A | N-(alpha-acyloxyethyl) compound and method for the preparation thereof | SHIN-ETSU VINYL ACETATE CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0703219-A1 | Method for the preparation of an N-vinyl compound | SHIN-ETSU VINYL ACETATE CO., LTD. (JP) | 1996-03-27 | — | — | EP | disclosed |
| EP-0699664-A1 | N-(aLpha-acyloxyethyl) compound and method for the preparation thereof | SHIN-ETSU VINYL ACETATE CO., LTD. (JP) | 1996-03-06 | — | — | EP | disclosed |