Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.32 |
| ▸ | DUT | P33316 | 1/20 | 0.31 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3927922 | 0.97 | TYMP (0.37) | TYMPP2RY14P2RY2P2RY4P2RY6 | |
| SCHEMBL13715716 | 0.97 | TYMP (0.37) | TYMPP2RY14P2RY2P2RY4P2RY6 | |
| SCHEMBL6932021 | 0.96 | TYMP (0.35) | TYMPP2RY14P2RY2P2RY4P2RY6 | |
| SCHEMBL6933190 | 0.95 | TYMP (0.35) | TYMPP2RY14P2RY2P2RY4P2RY6 | |
| SCHEMBL22073385 | 0.95 | P2RY2 (0.37) | TYMPP2RY14P2RY2P2RY4P2RY6 | |
| SCHEMBL2106163 | 0.94 | TYMP (0.36) | TYMPP2RY14P2RY2P2RY4P2RY6 | |
| SCHEMBL24878605 | 0.94 | TYMP (0.37) | TYMPP2RY14P2RY2P2RY4P2RY6 | |
| SCHEMBL13493921 | 0.94 | TYMP (0.37) | TYMPP2RY14P2RY2P2RY4P2RY6 | |
| SCHEMBL1539684 | 0.94 | TYMP (0.37) | TYMPP2RY14P2RY2P2RY4P2RY6 | |
| SCHEMBL17220688 | 0.94 | TYMP (0.37) | TYMPP2RY14P2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651759-B1 | NOVEL 2'-O-ALKYL NUCLEOSIDES AND PHOSPHORAMIDITES PROCESSES FOR THE PREPARATION AND USES THEREOF | ISIS PHARMACEUTICALS INC (US) | 2003-12-10 | — | — | EP | disclosed |
| EP-1223173-A2 | Novel 2'-O-alkyl nucleosides and phosphoramidites processes for the preparation and uses thereof | ISIS PHARMACEUTICALS, INC. (US) | 2002-07-17 | — | — | EP | disclosed |
| US-6242592-B1 | Process for the preparation of 2′-O-alkyl-guanosine, cytidine, and uridine phosphoramidites | ISIS PHARMACEUTICALS, INC. | 2001-06-05 | — | — | US | disclosed |
| US-6133438-A | Process for the preparation of 2'-O-alkyl purine phosphoramidites | ISIS PHARMACEUTICALS, INC. (US) | 2000-10-17 | — | — | US | disclosed |
| US-5856466-A | Process for the preparation of 2'-O-alkyl purine phosphoramidites | ISIS PHARMACEUTICALS, INC. (US) | 1999-01-05 | — | — | US | disclosed |
| US-5646265-A | Process for the preparation of 2'-O-alkyl purine phosphoramidites | ISIS PHARMCEUTICALS, INC. (US) | 1997-07-08 | — | — | US | disclosed |