SCHEMBL6933873

SCHEMBL6933873

CCOC1=NN(C(C)C)C(=O)C1(O)O

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6934456 0.81 GAA (0.32) GAATDP1PDE4APDE4BPDE4C
SCHEMBL6935653 0.76 ELANE (0.31)
SCHEMBL6928265 0.71 GAA (0.39) GAATDP1
SCHEMBL6933456 0.70 GAA (0.30) GAATDP1
SCHEMBL6933866 0.67 GAA (0.32) GAATDP1
SCHEMBL20284326 0.67 TDP1 (0.53) GAATDP1
SCHEMBL6931334 0.67 GAA (0.32) GAATDP1
SCHEMBL6934819 0.61
SCHEMBL6933587 0.60
SCHEMBL6930216 0.56 GAA (0.31) GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5958382-A ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR SOCIETE L'OREAL S.A. (FR) 1999-09-28 US claimed
EP-0903342-B1 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics OREAL (FR) 2003-12-17 EP disclosed
US-5958382-A ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR SOCIETE L'OREAL S.A. (FR) 1999-09-28 US disclosed
EP-0903342-A1 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics L'OREAL (FR) 1999-03-24 EP disclosed