SCHEMBL6934116

SCHEMBL6934116

CC(=NOCCOc1ccc(CC(Oc2ccccc2)C(=O)O)cc1)c1ccc(-c2ccccn2)cc1

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.53
PPARA Q07869 17/20 0.53
PPARD Q03181 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6934112 1.00 PPARG (0.53) PPARGPPARAPPARD
SCHEMBL5609777 0.96 PPARG (0.53) PPARGPPARAPPARD
SCHEMBL5609772 0.96 PPARG (0.53) PPARGPPARAPPARD
SCHEMBL5615680 0.96 PPARG (0.53) PPARGPPARAPPARD
SCHEMBL5609017 0.95 PPARG (0.50) PPARGPPARAPPARD
SCHEMBL5609830 0.95 PPARG (0.53) PPARGPPARA
SCHEMBL5609836 0.95 PPARG (0.53) PPARGPPARA
SCHEMBL5609020 0.95 PPARG (0.50) PPARGPPARAPPARD
SCHEMBL5609766 0.93 PPARG (0.49) PPARGPPARAPPARD
SCHEMBL5609761 0.93 PPARG (0.49) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0916651-B1 PHENYLALKYLCARBOXYLIC ACID DERIVATIVES SANKYO CO (JP) 2003-10-15 EP claimed
US-6103907-A ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT SANKYO COMPANY, LIMITED (JP) 2000-08-15 US claimed
CN-1219927-A Phenylalkylcarboxylic acid derivatives SANKYO CO (JP) 1999-06-16 CN claimed
EP-0916651-A1 PHENYLALKYLCARBOXYLIC ACID DERIVATIVES Sankyo Company, Limited (JP) 1999-05-19 EP claimed
EP-0916651-B1 PHENYLALKYLCARBOXYLIC ACID DERIVATIVES SANKYO CO (JP) 2003-10-15 EP disclosed
US-6103907-A ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT SANKYO COMPANY, LIMITED (JP) 2000-08-15 US disclosed
CN-1219927-A Phenylalkylcarboxylic acid derivatives SANKYO CO (JP) 1999-06-16 CN disclosed
EP-0916651-A1 PHENYLALKYLCARBOXYLIC ACID DERIVATIVES Sankyo Company, Limited (JP) 1999-05-19 EP disclosed