Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 4/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.34 |
| ▸ | VHL | P40337 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032330 | 0.84 | ATM (0.61) | ATMACEMMEVHLPIK3CD | |
| SCHEMBL4254729 | 0.84 | ATM (0.61) | ATMACEMMEVHLPIK3CD | |
| SCHEMBL2032328 | 0.84 | ATM (0.61) | ATMACEMMEVHLPIK3CD | |
| SCHEMBL4250847 | 0.84 | ATM (0.61) | ATMACEMMEVHLPIK3CD | |
| SCHEMBL683107 | 0.84 | ATM (0.56) | ATMACEMME | |
| SCHEMBL29430243 | 0.84 | ATM (0.56) | ATMACEMMEDPP4DPP8 | |
| SCHEMBL4258847 | 0.84 | ATM (0.61) | ATMACEMMEVHLPIK3CD | |
| SCHEMBL4250843 | 0.84 | ATM (0.61) | ATMACEMMEVHLPIK3CD | |
| SCHEMBL7374992 | 0.84 | ATM (0.56) | ATMACEMME | |
| SCHEMBL4252592 | 0.84 | ATM (0.61) | ATMACEMMEVHLPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009420-B1 | CONJUGATES USEFUL IN THE TREATMENT OF PROSTATE CANCER | MERCK & CO INC (US) | 2003-12-17 | — | — | EP | disclosed |