Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364884 | 0.88 | POLB (0.60) | ARPOLBMAPTKDM4EKMT2A | |
| SCHEMBL13991656 | 0.88 | AR (0.56) | ARPOLBKDM4EALDH1A1TDP1 | |
| SCHEMBL19827604 | 0.86 | AR (0.67) | ARPOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL14174325 | 0.84 | AR (0.65) | ARPOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL16232989 | 0.83 | AR (0.82) | ARPOLBMAPTKDM4EALDH1A1 | |
| Ralaniten Acetate SCHEMBL16232961 | 0.83 | AR (1.00) | ARPOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL16226899 | 0.83 | AR (0.82) | ARPOLBMAPTKDM4EALDH1A1 | |
| Ralaniten Acetate SCHEMBL16232958 | 0.83 | AR (1.00) | ARPOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL16226900 | 0.83 | AR (0.82) | ARPOLBMAPTKDM4EALDH1A1 | |
| Ralaniten Acetate SCHEMBL16232963 | 0.83 | AR (1.00) | ARPOLBMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |